Synthesis and application of functional nanocarriers
In this group, we aim at the development of new functional nanomaterials with a focus on the encapsulation of active compounds. During the development process, the first step is the synthesis of the colloidal base material, which can be covalently crosslinked structures like nanocapsules or self-assembled vesicular systems. Additionally, the encapsulated compounds vary from small drugs or contrast agents to whole groups of molecules needed for a chemical or enzymatic reaction. Finally, the surface of the nanocarriers is engineered to achieve additional properties like targeting abilities for a directed transport. On the way, many different factors like shell crosslinking, release profiles and degradability need to be optimized in order to obtain the desired functions. These functions ultimately range from targeted drug delivery to the installation of nanoreactors.