Sharafudheen Pottanam Chali
Max Planck Institute for Polymer Research
Main Focus
His research interest ranges from the design and synthesis of nanocapsules via miniemulsification, encapsulation of hydrophilic and hydrophobic therapeutic components, in vivo applications and nanocapsules as synthetic organelles.
Curriculum Vitae
Sharafudheen Pottanam Chali graduated (BS-MS) with distinction in 2018 from the Indian Institute of Science Education and Research (IISER) Pune, India and obtained his Ph.D. degree in Natural Science from the University of Muenster, Germany, in August 2021, within the CiM-IMPRS graduate program (Cells in Motion Interfaculty Centre-International Max Planck Research School). During his Ph.D. he worked on biodegradable supramolecular polymer nanocarriers for intracellular delivery applications under the guidance of Prof. Bart Jan Ravoo. In September 2021, he joined the Department of Physical Chemistry of Polymers at the Max Planck Institute for Polymer Research (MPI-P) as a postdoctoral researcher, working with Prof. Katharina Landfester. In 2024, he was promoted to project coordinator of the Nanocapsules subgroup in the department.
Selected Publications
Pottanam Chali S, Ravoo BJ, Polymer nanocontainers for intracellular delivery. Angew. Chem. Int. Ed. 2020, 59, 2962-2972.
Kudruk S,+ Pottanam Chali S,+ Matos A L L, Bourque C, Dunker C, Gatsogiannis C, Ravoo BJ,* Gerke V,* Biodegradable and dual responsive polypeptide-shelled cyclodextrin-containers for intracellular delivery of membrane-impermeable cargo. Adv. Sci. 2021, 2100694. (+equal contribution)
Pottanam Chali S, Hüwel S, Rentmeister A,* Ravoo BJ,* Self assembled cationic polypeptide supramolecular nanogels for intracellular DNA delivery. Chem. Eur. J. 2021, 27, 12198-12206.
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Pottanam Chali S, Azhdari S, Galstyan A, Gröschel A H, Ravoo BJ,* Biodegradable supramolecular micelles via host-guest interaction of cyclodextrin terminated polypeptides and adamantane terminated polycaprolactones. Chem. Comm. 2021, 57, 9446-9449.