Director

Prof. Dr.  Katharina Landfester
Prof. Dr. Katharina Landfester
Director
Phone:+49 6131 379-170

CV and Research Interest

Media

Science meets art

The guest commentary by Prof. Katharina Landfester on "Chemistry of colours" at the Städel Museum in Frankfurt is now online.
Prof. Katharina Landfester had a TV show appearance at 3Sat Scobel.

Talkshow and documentary about plastics

Prof. Katharina Landfester had a TV show appearance at 3Sat Scobel. [more]

News

On 26.09.2019, Olga Koshkina presented a talk "Controlled Synthesis of Perfluorocarbon-loaded Polymeric Nanoparticles for 19F MRI: from the Bench towards the Clinics" at the 3rd Molecular Imaging Symposium MoBi 2019 in Münster.

Conference contribution

On 26.09.2019, Olga Koshkina presented a talk "Controlled Synthesis of Perfluorocarbon-loaded Polymeric Nanoparticles for 19F MRI: from the Bench towards the Clinics" at the 3rd Molecular Imaging Symposium MoBi 2019 in Münster.
On October 1st, 2019, the EU project AlternativesToGd started in which we participate as a partner.
On October 1st, 2019, the EU project AlternativesToGd started in which we participate as a partner.
The Max Planck Institute for Polymer Research (MPIP, Germany) and the Vidyasirimedhi Institute of Science and Technology (VISTEC, Thailand) opened the 1^st Max Planck Partner Laboratory of Thailand. The newly founded International Research Center is headed by Assoc. Prof. Daniel Crespy and will focus on the creation of sustainable polymer materials. Prof. Dr. Katharina Landfester, Prof. Dr. Volker Mailaender, Dr. Heloise Therien-Aubin, and Dr. Manfred Wagner participated to the opening ceremony on the 03 October 2019. The Max Planck-VISTEC Partner Laboratory has successfully gathered scientific and financial commitments from VISTEC and the MPIP to ensure a long term and fruitful collaboration between both institutes.
The Max Planck Institute for Polymer Research (MPIP, Germany) and the Vidyasirimedhi Institute of Science and Technology (VISTEC, Thailand) opened the 1^st Max Planck Partner Laboratory of Thailand. The newly founded International Research Center is headed by Assoc. Prof. Daniel Crespy and will focus on the creation of sustainable polymer materials. Prof. Dr. Katharina Landfester, Prof. Dr. Volker Mailaender, Dr. Heloise Therien-Aubin, and Dr. Manfred Wagner participated to the opening ceremony on the 03 October 2019. The Max Planck-VISTEC Partner Laboratory has successfully gathered scientific and financial commitments from VISTEC and the MPIP to ensure a long term and fruitful collaboration between both institutes.
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We are delighted to have Prof. Yanlei Yu and Prof. Jia Wei from Fudan University for their visit.
We are delighted to have Prof. Yanlei Yu and Prof. Jia Wei from Fudan University for their visit.
Domenik Prozeller successfully passed his Ph.D. examination in September 2019.

Ph.D. examination successfully passed

Domenik Prozeller successfully passed his Ph.D. examination in September 2019.
On the 19.09.2019 Andreas Riedinger presented a talk "Kinetically Driven Self-Assembly of Semiconductor Nanoplatelets" at the NaNaX9 conference in Hamburg.
On the 19.09.2019 Andreas Riedinger presented a talk "Kinetically Driven Self-Assembly of Semiconductor Nanoplatelets" at the NaNaX9 conference in Hamburg.
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"Dr. Banu Iyisan gave a talk about "Temperature Sensing in Cells by Polymeric Upconversion Nanocapsules" at the 33rd Conference of the European Colloid and Interface Society (ECIS) ECIS in Leuven (Belgium)."

Conference contribution

"Dr. Banu Iyisan gave a talk about "Temperature Sensing in Cells by Polymeric Upconversion Nanocapsules" at the 33rd Conference of the European Colloid and Interface Society (ECIS) ECIS in Leuven (Belgium)."
We welcome Yun Gao and Xiaojie Yin in Kai Zhang's group, both coming from the Shanghai University where they work in the group of our former group member Liping Lv.
We welcome Yun Gao and Xiaojie Yin in Kai Zhang's group, both coming from the Shanghai University where they work in the group of our former group member Liping Lv.
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Katharina Landfester together with Ilke Sentürk and Oksana Suraeva was at the ACS Fall 2019 meeting in San Diego. All three of them gave interesting talks at the meeting.
Katharina Landfester together with Ilke Sentürk and Oksana Suraeva was at the ACS Fall 2019 meeting in San Diego. All three of them gave interesting talks at the meeting.
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Fei Chen successfully passed his Ph.D. examination in August 2019.

Ph.D. examination successfully passed

Fei Chen successfully passed his Ph.D. examination in August 2019.
On the 2019 Microscopy & Microanalysis conference in Portland, USA, Shen Han was rewarded the Studend Scholar Award for his contribion on “High-Contrast Imaging of Nanodiamonds in Cells by Energy filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis”

Student Scholar Award

On the 2019 Microscopy & Microanalysis conference in Portland, USA, Shen Han was rewarded the Studend Scholar Award for his contribion on “High-Contrast Imaging of Nanodiamonds in Cells by Energy filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis”
[more]
At the 16th European Conference on Organized Films, which was held in Paris, France from July 8-12, 2019, Dr. Andreas Riedinger shared his research.

Conference contribution

At the 16th European Conference on Organized Films, which was held in Paris, France from July 8-12, 2019, Dr. Andreas Riedinger shared his research. [more]
At the Zsigmondy Colloquium 2019, which was held in Dresden, Germany from July 10-12, Henry Halim shared his work in a talk about "Water transferred semiconductor nanoplatelets as ultra-bright fluorescent probes".

Contribution at Zsigmondy Colloquium

At the Zsigmondy Colloquium 2019, which was held in Dresden, Germany from July 10-12, Henry Halim shared his work in a talk about "Water transferred semiconductor nanoplatelets as ultra-bright fluorescent probes".
[more]
Dr. Johanna Simon received the renowned Otto Hahn Award of the Max Planck Society for her dissertation on "Proteomic characterization of the biomolecular corona and its impact on targeted drug delivery via nanocarriers". The prize includes a scientific stay abroad of up to two years. Afterwards, she will be able to set up her own research group at a Max Planck Institute of her choice. The Otto Hahn Award is granted annually to a maximum of four young scientists for outstanding achievements in their dissertations. It is intended to pave the way for a long-term scientific career.

Otto Hahn Award

Dr. Johanna Simon received the renowned Otto Hahn Award of the Max Planck Society for her dissertation on "Proteomic characterization of the biomolecular corona and its impact on targeted drug delivery via nanocarriers". The prize includes a scientific stay abroad of up to two years. Afterwards, she will be able to set up her own research group at a Max Planck Institute of her choice. The Otto Hahn Award is granted annually to a maximum of four young scientists for outstanding achievements in their dissertations. It is intended to pave the way for a long-term scientific career.
At the European Polymer Congress, which was held in Crete, Greece from June 9-14, 2019, Cyrine Ayed presented her work on “Visible light-promoted photocatalytic carbon-carbon double bond cleavage over conjugated microporous polymers in aqueous medium”.

Contribution to the European Polymer Congress 2019

At the European Polymer Congress, which was held in Crete, Greece from June 9-14, 2019, Cyrine Ayed presented her work on “Visible light-promoted photocatalytic carbon-carbon double bond cleavage over conjugated microporous polymers in aqueous medium”.

Catalysis Towards Greener Chemistry

Dr. Kai Zhang was invited to give a talk on “Designing conjugated polymers for visible light-promoted heterogeneous photocatalysis” at the 2nd IMPRS-RECHARGE Symposium on “Catalysis Towards Greener Chemistry”, which was held at the Max-Planck-Institut für Kohlenforschung from May 20-23, 2019 in Mühlheim, Germany.

Contribution to E-MRS meeting 2019

At the E-MRS spring meeting 2019, which was held in Nice, France from May 27-31, Rebecca Momper shared her work in a talk about "Kinetically driven self-assembly of semiconductor nanoplatelets".
We are happy that our recent article about "Prevention of Dominant IgG Adsorption on Nanocarriers in IgG-enriched Blood Plasma by Clusterin Precoating" by Domenik Prozeller et al. is featured on the back cover of Advanced Science.

Featured on the cover!

We are happy that our recent article about "Prevention of Dominant IgG Adsorption on Nanocarriers in IgG-enriched Blood Plasma by Clusterin Precoating" by Domenik Prozeller et al. is featured on the back cover of Advanced Science. [more]

Presentations at the ACS spring meeting 2019

Two of our group members contributed to the ACS spring meeting, which was held in Orlando, Florida from March 31 - April 4, 2019: Marie-Luise Frey gave a talk about "Glycodendron modified HES nanocapsules for targeting of dendritic cells" and Tassilo Gleede talked about "Living anionic polymerization of aziridines tolerates water and gives fast access to amphiphilic multi-block copolymers".
© Royal Society of Chemistry 2017Our article titled ‘Fully degradable protein nanocarriers by orthogonal photoclick tetrazole/ene chemistry for the encapsulation and release’ has been selected to be a part of the first Horizons Community Board online article collection on nanobiomedicine.

Article in Themed Collection!

© Royal Society of Chemistry 2017

Our article titled ‘Fully degradable protein nanocarriers by orthogonal photoclick tetrazole/ene chemistry for the encapsulation and release’ has been selected to be a part of the first Horizons Community Board online article collection on nanobiomedicine. [more]
Katharina Landfester contributed with the chapter "Introduction to biophysics and medical physics" to the book "Vielfältige Physik" ("Diverse Physics"). In this book more than 30 female scientists in physics and chemistry provide surprising insights into their current research, vividly explain complex facts and make newly discovered phenomena of modern physics understandable.

Contribution in "Vielfältige Physik"

Katharina Landfester contributed with the chapter "Introduction to biophysics and medical physics" to the book "Vielfältige Physik" ("Diverse Physics"). In this book more than 30 female scientists in physics and chemistry provide surprising insights into their current research, vividly explain complex facts and make newly discovered phenomena of modern physics understandable.
Dr. Kai Zhang has been appointed to Associate Editor by the journal Polymer International (Wiley-VCH).

Dr. Kai Zhang has been appointed to Associate Editor by the journal Polymer International (Wiley-VCH).
In the book "Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches", our group has two contributions: Banu Iyisan and Katharina Landfester wrote the chapter about "Polymeric Nanoparticles" and Lorna Moll and Volker Mailänder about "Nanocarriers and Immune Cells".

Book contribution in "Biological Responses to Nanoscale Particles"

In the book "Biological Responses to Nanoscale Particles: Molecular and Cellular Aspects and Methodological Approaches", our group has two contributions:
Banu Iyisan and Katharina Landfester wrote the chapter about "Polymeric Nanoparticles" and Lorna Moll and Volker Mailänder about "Nanocarriers and Immune Cells".
Niklas Huber, PhD student in our department has been selected as junior member into the Gutenberg Academy at Johannes Gutenberg University Mainz (JGU).
Congratulations!

Membership of Gutenberg Academy

Niklas Huber, PhD student in our department has been selected as junior member into the Gutenberg Academy at Johannes Gutenberg University Mainz (JGU).

Congratulations!

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Dr. Kai Zhang has been appointed to full professor by Fudan University, Shanghai.

Full Professorship for Dr. Kai Zhang

Dr. Kai Zhang has been appointed to full professor by Fudan University, Shanghai.
Milagro Mottola has been granted a DAAD short-term scholarship.

Congratulations!

Milagro Mottola has been granted a DAAD short-term scholarship.
Zhiaoliang Zheng, PhD, has been granted a Marie Curie fellowship.

Congratulations!

Zhiaoliang Zheng, PhD, has been granted a Marie Curie fellowship.
Dr. Frederik R. Wurm received the EPJ Award 2019, which was awarded during the 6th International Symposium Frontiers in Polymer Science. Zoom Image
Dr. Frederik R. Wurm received the EPJ Award 2019, which was awarded during the 6th International Symposium Frontiers in Polymer Science.
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Ph.D. examination successfully passed

Hisaschi Tee successfully passed his Ph.D. examination in April 2019.

Prof. Dr. Katharina Landfester - Physical Chemistry of Polymers


Welcome to the Department of Physical Chemistry of Polymers

We view it as our mission to create colloids with increasingly specific and complex properties for new materials and bio-medical applications and to use the confinement of stable nanodroplets to tune chemical reactions and transformation processes. Particles suspended in a liquid, known as a colloid, are versatile and flexible in their uses. They are found everywhere in our daily lives, from mother's milk to adhesives and automobile paint to the most modern technologies. The special properties of colloids can therefore be adapted in each case to the intended purpose. That facilitates the enormous versatility of the miniemulsion process. From the encapsulation of dedicated molecules, like drugs, self-healing agents etc. through to generation of extremely small nanostructures, these simple spheres can be utilised with a highly uniform size and a defined functionality of the surface. The significance of the miniemulsion technique is that it is possible to use a wide variety of polymerization techniques with a wide range of monomers. Hereby important factors like size, shape, degradation, release kinetics, surface functionalization can be precisely tuned as requested. The continual progress in knowledge about the properties of nanoscale objects and their interactions with living tissue like cells or with electromagnetic radiation opens diverse opportunities. 

1.
Beatriz C. Ma, Lucas Caire da Silva, Seong-Min Jo, Frederik R. Wurm, Markus B. Bannwarth, Kai A. I. Zhang, Kai Sundmacher, Katharina Landfester
Polymer-Based Module for NAD+ Regeneration with Visible Light
DOI
Regeneration of NAD+ from NADH has been achieved using a completely synthetic functional module. Our module consisted of photocatalytic conjugated polymer nanoparticles encapsulated in cell-sized polymer vesicles, which offered chemical and physical protection to the reaction centers. We also demonstrate that the efficiency of simultaneous NAD-regeneration and enzymatic reactions is dramatically improved when the enzyme is surrounded by a protective silica shell.
Regeneration of NAD+ from NADH has been achieved using a completely synthetic functional module. Our module consisted of photocatalytic conjugated polymer nanoparticles encapsulated in cell-sized polymer vesicles, which offered chemical and physical protection to the reaction centers. We also demonstrate that the efficiency of simultaneous NAD-regeneration and enzymatic reactions is dramatically improved when the enzyme is surrounded by a protective silica shell.
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2.
Shen Han, Marco Raabe, Lorna Hodgson, Judith Mantell, Paul Verkade, Theo Lasser, Katharina Landfester, Tanja Weil, and Ingo Lieberwirth
High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis
DOI
For the first time, our group has succeeded in imaging individual nanodiamonds that have been taken up by a living cell. Two different microscopy techniques were combined to achieve a unique identification of the nanodiamonds. The article is published in the journal Nano Letters: “High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis”.
For the first time, our group has succeeded in imaging individual nanodiamonds that have been taken up by a living cell. Two different microscopy techniques were combined to achieve a unique identification of the nanodiamonds. The article is published in the journal Nano Letters: “High-Contrast Imaging of Nanodiamonds in Cells by Energy Filtered and Correlative Light-Electron Microscopy: Toward a Quantitative Nanoparticle-Cell Analysis”.
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3.
C. T. J. Ferguson, N. Huber, K. Landfester, K. A. I. Zhang
Dual-Responsive Photocatalytic Polymer Nanogels
DOI
4.
A. Ghazaryan, K. Landfester, V. Mailänder
Protein deglycosylation can drastically affect the cellular uptake
DOI
5.
M. Hu, H.-J. Butt, K. Landfester, M. B. Bannwarth, S. Wooh, H. Thérien-Aubin
Shaping the Assembly of Superparamagnetic Nanoparticles
DOI
6.
J. Fischer, S. Beckers, D. Yiamsawas, E. Thines, K. Landfester, F. R. Wurm
Targeted Drug Delivery in Plants: Enzyme-Responsive Lignin Nanocarriers for the Curative Treatment of the Worldwide Grapevine Trunk Disease Esca
DOI
7.
D. Xu, S. Bartelt, S. Rasoulinejad, F. Chen, S. V. Wegner
Green light lithography: a general strategy to create active protein and cell micropatterns
DOI
8.
T. Haider, C. Völker, J. Kramm, K. Landfester, F. R. Wurm
Plastics of the Future? The Impact of Biodegradable Polymers on the Environment and on Society
DOI
9.
D. Prozeller, J. Pereira, J. Simon, V. Mailänder, S. Morsbach, K. Landfester
Prevention of Dominant IgG Adsorption on Nanocarriers in IgG-Enriched Blood Plasma by Clusterin Precoating
DOI
10.
J. Byun, K. Landfester, K. A. I. Zhang
Conjugated Polymer Hydrogel Photocatalysts with Expandable Photoactive Sites in Water
DOI
11.
C. Ayed, L. Caire da Silva, D. Wang, K. A. I. Zhang
Designing conjugated microporous polymers for visible light-promoted photocatalytic carbon-carbon double bond cleavage in aqueous medium
DOI
12.
M. Tonigold, J. Simon, D. Estupinan, M. Kokkinopoulou, J. Reinholz, U. Kintzel, A. Kaltbeizel, P. Renz, M.P. Domogalla, K. Steinbrink, I. Lieberwirth, D. Crespy, K. Landfester, V. Mailänder
Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona
DOI

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