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VERSION:2.0
PRODID:icalendar-ruby
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METHOD:PUBLISH
BEGIN:VEVENT
DTSTAMP:20261015T044809Z
UID:https://www.mpip-mainz.mpg.de/events/28153/536464
DTSTART:20210504T130000Z
DTEND:20210504T140000Z
CLASS:PUBLIC
CREATED:20210430T085222Z
DESCRIPTION:Accurate structural models of biological systems can be obtaine
 d by integrative approaches that properly combine multiple sources of info
 rmation\, such as experimental data and a priori physico-chemical knowledg
 e. In this talk\, I will give an overview of the methodological approaches
  that we have been developing as well as a series of applications to syste
 ms of outstanding biological importance. Specifically\, I will focus on th
 e determination of structural ensembles of intrinsically disordered system
 s using NMR data and on the use of cryo-electron microscopy data to unrave
 l the continuous dynamics of flexible parts of ordered systems. Finally\, 
 I will present an open-source\, freely-available module of the PLUMED libr
 ary (www.plumed.org)\, which enables the simultaneous determination of str
 ucture and dynamics of conformationally heterogeneous systems by integrati
 ng experimental data with a priori information.\nVortragende(r): Prof. Mas
 similiano Bonomi
LAST-MODIFIED:20210430T114144Z
LOCATION:Digital
ORGANIZER;CN=Omar Valsson:mailto:valsson@mpip-mainz.mpg.de
SUMMARY:Methods and applications in integrative structural biology
URL;VALUE=URI:https://www.mpip-mainz.mpg.de/events/28153/536464
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