Publications | Makromolecular Therapeutics Group Prof. Dr. Lutz Nuhn

Bros, M.; Nuhn, L.; Simon, J.; Moll, L.; Mailänder, V.; Landfester, K.; Grabbe, S.: The Protein Corona as a Confounding variable of nanoparticle-Mediated Targeted vaccine Delivery. Frontiers in immunology 9, 1760 (2018)

Lybaert, L.; Vermaelen, K.; De Geest, B. G.; Nuhn, L.: Immunoengineering through cancer vaccines - A personalized and multi-step vaccine approach towards precise cancer immunity. Journal of Controlled Release 289, pp. 125 - 145 (2018)

Nuhn, L.; Bolli, E.; Massa, S.; Vandenberghe, I.; Movahedi, K.; Devreese, B.; Van Ginderachter, J. A.; De Geest, B. G.: Targeting Protumoral Tumor-Associated Macrophages with Nanobody-Functionalized Nanogels through Strain Promoted Azide Alkyne Cycloaddition Ligation. Bioconjugate Chemistry 29 (7), pp. 2394 - 2405 (2018)

Nuhn, L.; De Koker, S.; Van Lint, S.; Zhong, Z.; Catani, J. P.; Combes, F.; Deswarte, K.; Li, Y.; Lambrecht, B. N.; Lienenklaus, S. et al.; Sanders, N. N.; David, S. A.; Tavernier, J.; De Geest, B. G.: Nanoparticle-Conjugate TLR7/8 Agonist Localized Immunotherapy Provokes Safe Antitumoral Responses. Advanced Materials 30 (45), 1803397 (2018)

Nuhn, L.; Van Herck, S.; Best, A.; Deswarte, K.; Kokkinopoulou, M.; Lieberwirth, I.; Koynov, K.; Lambrecht, B. N.; De Geest, B. G.: FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles. Angewandte Chemie International Edition 57 (33), pp. 10760 - 10764 (2018)

Nuhn, L.; Van Hoecke, L.; Deswarte, K.; Schepens, B.; Li, Y. P.; Lambrecht, B. N.; De Koker, S.; David, S. A.; Saelens, X.; De Geest, B. G.: Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist. Biomaterials 178, pp. 643 - 651 (2018)

Van Driessche, A.; Kocere, A.; Everaert, H.; Nuhn, L.; Van Herck, S.; Griffiths, G.; Fenaroli, F.; De Geest, B. G.: pH-Sensitive Hydrazone-Linked Doxorubicin Nanogels via Polymeric-Activated Ester Scaffolds: Synthesis, Assembly, and In Vitro and In Vivo Evaluation in Tumor-Bearing Zebrafish. Chemistry of Materials 30 (23), pp. 8587 - 8596 (2018)

Van Herck, S.; Deswartep, K.; Nuhn, L.; Zhong, Z.; Catani, J. P. P.; Li, Y.; Sanders, N. N.; Lienenklaus, S.; De Koker, S.; Lambrecht, B. N. et al.; David, S. A.; De Geest, B. G.: Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates. Journal of the American Chemical Society 140 (43), pp. 14300 - 14307 (2018)

Van Herck, S.; Van Hoecke, L.; Louage, B.; Lybaert, L.; De Coen, R.; Kasmi, S.; Esser-Kahn, A. P.; David, S. A.; Nuhn, L.; Schepens, B. et al.; Saelens, X.; De Geest, B. G.: Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant. Bioconjugate Chemistry 29 (3), pp. 748 - 760 (2018)