Dr. Hans-Joachim Räder

Hans Joachim Räder studied chemistry at the University of Mainz. He obtained his Diploma in 1987 with Prof. K. Müllen on a synthetic approach to new heterocyclic fulvalene-type donor structures for conducting organic metals. From 1988 to 1991 he worked for his Ph. D. thesis in the field of electrochemistry. Using cyclic voltammetry, he investigated the redox behavior of extended p-systems which can be used as model compounds for conjugated polymers. In 1990 he moved with the group of Prof. K. Müllen to the Max-Planck-Institute for Polymer Research, where he was responsible for projects on redox-chemistry and heterocyclic donors. Presently he is the head of mass-spectrometric division, which he established in 1991. 

Research interests: Mass Spectrometry of Macromolecules

Our research involves the methodical development of matrix assisted laser desorption/ ionization time-of-flight mass spectrometry (MALDI-TOF MS) in the analysis of synthetic polymers, ion soft landing of intractable macromolecules, pulsed laser deposition (PLD) of unsublimable polycyclic aromatic hydrocarbons (PAHs) and investigation of complex structures by ion mobility mass spectrometry. Special interests were elucidation of desorption and ionization behavior of conjugated polymers, giant PAHs, analysis of intractable samples and gas phase structure elucidation of macrocycles and catenanes. Currently we explore the application of mass spectrometric imaging methods for organic electronic materials and murine tissue samples.

Selected Publications

Journal Article (36)

1.
Journal Article
Ender, A. M.; Kaygisiz, K.; Räder, H. J.; Mayer, F. J.; Synatschke, C. V.; Weil, T.: Cell-Instructive Surface Gradients of Photoresponsive Amyloid-like Fibrils. ACS Biomaterials Science & Engineering 7 (10), pp. 4798 - 4808 (2021)
2.
Journal Article
Jung, S.; Fuchs, N.; Johe, P.; Wagner, A.; Diehl, E.; Yuliani, T.; Zimmer, C.; Barthels, F.; Zimmermann, R. A.; Klein, P. et al.; Waigel, W.; Meyr, J.; Opatz, T.; Tenzer, S.; Distler, U.; Räder, H. J.; Kersten, C.; Engels, B.; Hellmich, U. A.; Klein, J.; Schirmeister, T.: Fluorovinylsulfones and -Sulfonates as Potent Covalent Reversible Inhibitors of the Trypanosomal Cysteine Protease Rhodesain: Structure–Activity Relationship, Inhibition Mechanism, Metabolism, and In Vivo Studies. Journal of Medicinal Chemistry 64 (16), pp. 12322 - 12358 (2021)
3.
Journal Article
Bolli, E.; Scherger, M.; Arnouk, S. M.; Antunes, A. R. P.; Straßburger, D.; Urschbach, M.; Stickdorn, J.; De Vlaminck, K.; Movahedi, K.; Räder, H. J. et al.; Hernot, S.; Besenius, P.; Van Ginderachter, J. A.; Nuhn, L.: Targeted Repolarization of Tumor‐Associated Macrophages via Imidazoquinoline‐Linked Nanobodies. Advanced Science, 2004574 (2021)
4.
Journal Article
Scherger, M.; Räder, H. J.; Nuhn, L.: Self‐Immolative RAFT‐Polymer End Group Modification. Macromolecular Rapid Communications, 2000752 (2021)
5.
Journal Article
Abdulkarim, A.; Nathusius, M.; Bäuerle, R.; Strunk, K.-P.; Beck, S.; Räder, H. J.; Pucci, A.; Melzer, C.; Jänsch, D.; Freudenberg, J. et al.; Bunz, U. H. F.; Muellen, K.: Beyond p-Hexaphenylenes: Synthesis of Unsubstituted p-Nonaphenylene by a Precursor Protocol. Chemistry – A European Journal 27 (1), pp. 281 - 288 (2021)
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