Publikationen von Lutz Nuhn

Nuhn, L.; Van Herck, S.; Best, A.; Deswarte, K.; Kokkinopoulou, M.; Lieberwirth, I.; Koynov, K.; Lambrecht, B. N.; De Geest, B. G.: FRET Monitoring of Intracellular Ketal Hydrolysis in Synthetic Nanoparticles. Angewandte Chemie International Edition 57 (33), S. 10760 - 10764 (2018)

Nuhn, L.; Van Hoecke, L.; Deswarte, K.; Schepens, B.; Li, Y. P.; Lambrecht, B. N.; De Koker, S.; David, S. A.; Saelens, X.; De Geest, B. G.: Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist. Biomaterials 178, S. 643 - 651 (2018)

Van Driessche, A.; Kocere, A.; Everaert, H.; Nuhn, L.; Van Herck, S.; Griffiths, G.; Fenaroli, F.; De Geest, B. G.: pH-Sensitive Hydrazone-Linked Doxorubicin Nanogels via Polymeric-Activated Ester Scaffolds: Synthesis, Assembly, and In Vitro and In Vivo Evaluation in Tumor-Bearing Zebrafish. Chemistry of Materials 30 (23), S. 8587 - 8596 (2018)

Van Herck, S.; Deswartep, K.; Nuhn, L.; Zhong, Z.; Catani, J. P. P.; Li, Y.; Sanders, N. N.; Lienenklaus, S.; De Koker, S.; Lambrecht, B. N. et al.; David, S. A.; De Geest, B. G.: Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates. Journal of the American Chemical Society 140 (43), S. 14300 - 14307 (2018)

Van Herck, S.; Van Hoecke, L.; Louage, B.; Lybaert, L.; De Coen, R.; Kasmi, S.; Esser-Kahn, A. P.; David, S. A.; Nuhn, L.; Schepens, B. et al.; Saelens, X.; De Geest, B. G.: Transiently Thermoresponsive Acetal Polymers for Safe and Effective Administration of Amphotericin B as a Vaccine Adjuvant. Bioconjugate Chemistry 29 (3), S. 748 - 760 (2018)

Grymonpré, W.; Bostijn, N.; Herck, S.V.; Verstraete, G.; Vanhoorne, V.; Nuhn, L.; Rombouts, P.; Beer, T. D.; Remon, J.P.; Vervaet, C.: Downstream processing from hot-melt extrusion towards tablets: A quality by design approach. International Journal of Pharmaceutics 531 (1), S. 235 - 245 (2017)

Kasmi, S.; Louage, B.; Nuhn, L.; Verstraete, G.; Van Herck, S.; van Steenbergen, M. J.; Vervaet, C.; Hennink, W. E.; De Geest, B. G.: Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization. Polymer Chemistry 8 (42), S. 6544 - 6557 (2017)

Leber, N.; Kaps, L.; Aslam, M.; Schupp, J.; Brose, A.; Schäffel, D.; Fischer, K.; Diken, M.; Strand, D.; Koynov, K. et al.; Tuettenberg, A.; Nuhn, L.; Zentel, R.; Schuppan, D.: SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles. Journal of Controlled Release 248, S. 10 - 23 (2017)

Leber, N.; Nuhn, L.; Zentel, R.: Cationic Nanohydrogel Particles for Therapeutic Oligonucleotide Delivery. Macromolecular Bioscience 17 (10), 1700092 (2017)

Louage, B.; van Steenbergen, M. J.; Nuhn, L.; Risseeuw, M. D. P.; Karalic, I.; Winne, J.; Van Calenbergh, S.; Hennink, W. E.; De Geest, B. G.: Micellar Paclitaxel-Initiated RAFT Polymer Conjugates with Acid-Sensitive Behavior. ACS Macro Letters 6 (3), S. 272 - 276 (2017)

Lybaert, L.; Ryu, K. A.; Nuhn, L.; De Rycke, R.; De Wever, O.; Chon, A. C.; Esser-Kahn, A. P.; De Geest, B. G.: Cancer Cell Lysate Entrapment in CaCO3 Engineered with Polymeric TLR-Agonists: Immune-Modulating Microparticles in View of Personalized Antitumor Vaccination. Chemistry of Materials 29 (10), S. 4209 - 4217 (2017)

Vanparijs, N.; Nuhn, L.; De Geest, B. G.: Transiently thermoresponsive polymers and their applications in biomedicine. Chemical Society Reviews 46 (4), S. 1193 - 1239 (2017)

Verstraete, G.; Vandenbussche, L.; Kasmi, S.; Nuhn, L.; Brouckaert, D.; Renterghem, J. V.; Grymonpré, W.; Vanhoorne, V.; Coenye, T.; Geest, B.G. D. et al.; Beer, T. D.; Remon, J.P.; Vervaet, C.: Thermoplastic polyurethane-based intravaginal rings for prophylaxis and treatment of (recurrent) bacterial vaginosis. International Journal of Pharmaceutics 529 (1-2), S. 218 - 226 (2017)

De Coen, R.; Vanparijs, N.; Risseeuw, M. D. P.; Lybaert, L.; Louage, B.; De Koker, S.; Kumar, V.; Grooten, J.; Taylor, L.; Ayres, N. et al.; Van Calenbergh, S.; Nuhn, L.; De Geest, B. G.: pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting. Biomacromolecules 17 (7), S. 2479 - 2488 (2016)

Kasmi, S.; Louage, B.; Nuhn, L.; Van Driessche, A.; Van Deun, J.; Karalic, I.; Risseeuw, M.; Van Calenbergh, S.; Hoogenboom, R.; De Rycke, R. et al.; De Wever, O.; Hennink, W. E.; De Geest, B. G.: Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains. Biomacromolecules 17 (1), S. 119 - 127 (2016)

Louage, B.; Nuhn, L.; Risseeuw, M. D. P.; Vanparijs, N.; De Coen, R.; Karalic, I.; Van Calenbergh, S.; De Geest, B. G.: Well-Defined Polymer-Paclitaxel Prodrugs by a Grafting-from-Drug Approach. Angewandte Chemie, International Edition 55 (39), S. 11791 - 11796 (2016)

Lybaert, L.; Vanparijs, N.; Fierens, K.; Schuijs, M.; Nuhn, L.; Lambrecht, B. N.; De Geest, B. G.: A Generic Polymer-Protein Ligation Strategy for Vaccine Delivery. Biomacromolecules 17 (3), S. 874 - 881 (2016)

Nuhn, L.; Kaps, L.; Diken, M.; Schuppan, D.; Zentel, R.: Reductive Decationizable Block Copolymers for Stimuli-Responsive mRNA Delivery. Macromolecular Rapid Communications 37 (11), S. 924 - 933 (2016)

Nuhn, L.; Vanparijs, N.; De Beuckelaer, A.; Lybaert, L.; Verstraete, G.; Deswarte, K.; Lienenklaus, S.; Shukla, N. M.; Salyer, A. C. D.; Lambrecht, B. N. et al.; Grooten, J.; David, S. A.; De Koker, S.; De Geest, B. G.: pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation. Proceedings of the National Academy of Sciences of the United States of America 113 (29), S. 8098 - 8103 (2016)

Reichenwallner, J.; Thomas, A.; Nuhn, L.; Johann, T.; Meister, A.; Frey, H.; Hinderberger, D.: Tunable dynamic hydrophobic attachment of guest molecules in amphiphilic core-shell polymers. Polymer Chemistry 7 (37), S. 5783 - 5798 (2016)