Publications | Makromolecular Therapeutics Group Prof. Dr. Lutz Nuhn

De Coen, R.; Vanparijs, N.; Risseeuw, M. D. P.; Lybaert, L.; Louage, B.; De Koker, S.; Kumar, V.; Grooten, J.; Taylor, L.; Ayres, N. et al.; Van Calenbergh, S.; Nuhn, L.; De Geest, B. G.: pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting. Biomacromolecules 17 (7), pp. 2479 - 2488 (2016)

Kasmi, S.; Louage, B.; Nuhn, L.; Van Driessche, A.; Van Deun, J.; Karalic, I.; Risseeuw, M.; Van Calenbergh, S.; Hoogenboom, R.; De Rycke, R. et al.; De Wever, O.; Hennink, W. E.; De Geest, B. G.: Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains. Biomacromolecules 17 (1), pp. 119 - 127 (2016)

Louage, B.; Nuhn, L.; Risseeuw, M. D. P.; Vanparijs, N.; De Coen, R.; Karalic, I.; Van Calenbergh, S.; De Geest, B. G.: Well-Defined Polymer-Paclitaxel Prodrugs by a Grafting-from-Drug Approach. Angewandte Chemie, International Edition 55 (39), pp. 11791 - 11796 (2016)

Lybaert, L.; Vanparijs, N.; Fierens, K.; Schuijs, M.; Nuhn, L.; Lambrecht, B. N.; De Geest, B. G.: A Generic Polymer-Protein Ligation Strategy for Vaccine Delivery. Biomacromolecules 17 (3), pp. 874 - 881 (2016)

Nuhn, L.; Kaps, L.; Diken, M.; Schuppan, D.; Zentel, R.: Reductive Decationizable Block Copolymers for Stimuli-Responsive mRNA Delivery. Macromolecular Rapid Communications 37 (11), pp. 924 - 933 (2016)

Nuhn, L.; Vanparijs, N.; De Beuckelaer, A.; Lybaert, L.; Verstraete, G.; Deswarte, K.; Lienenklaus, S.; Shukla, N. M.; Salyer, A. C. D.; Lambrecht, B. N. et al.; Grooten, J.; David, S. A.; De Koker, S.; De Geest, B. G.: pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation. Proceedings of the National Academy of Sciences of the United States of America 113 (29), pp. 8098 - 8103 (2016)

Reichenwallner, J.; Thomas, A.; Nuhn, L.; Johann, T.; Meister, A.; Frey, H.; Hinderberger, D.: Tunable dynamic hydrophobic attachment of guest molecules in amphiphilic core-shell polymers. Polymer Chemistry 7 (37), pp. 5783 - 5798 (2016)

Vanparijs, N.; Nuhn, L.; Paluck, S. J.; Kokkinopoulou, M.; Lieberwirth, I.; Maynard, H. D.; De Geest, B. G.: Core/shell protein-reactive nanogels via a combination of RAFT polymerization and vinyl sulfone postmodification. Nanomedicine 11 (20), pp. 2631 - 2645 (2016)

Zhang, Z.; Schepens, B.; Nuhn, L.; Saelens, X.; Schotsaert, M.; Callewaert, N.; De Rycke, R.; Zhang, Q.; Moins, S.; Benali, S. et al.; Mespouille, L.; Hoogenboom, R.; De Geest, B. G.: Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination. Chemical Communications 52 (16), pp. 3352 - 3355 (2016)

Zhang, Z.; Vanparijs, N.; Vandewalle, S.; Du Prez, F. E.; Nuhn, L.; De Geest, B. G.: Squaric ester amides as hydrolysis-resistant functional groups for protein-conjugation of RAFT-derived polymers. Polymer Chemistry 7 (47), pp. 7242 - 7248 (2016)

De Coen, R.; Nuhn, L.; De Geest, B.: Acid-degradable, mannosylated nanogels for dendritic cell targeting. In Abstracts of Papers of the American Chemical Society, 251 (PMSE), 118. 251st ACS National Meeting, San Diego, CA, March 13, 2016 - March 17, 2016. (2016)

Kaps, L.; Leber, N.; Aslam, M.; Brose, A.; Nuhn, L.; Schupp, J.; Zentel, R.; Schuppan, D.; Tuttenberg, A.; Diken, M.: In vivo gene silencing in the liver: Comparison of siRNA-loaded non biodegradable vs. biodegradable nanohydrogel particles for antifibrotic therapy. In Hepatology, 64 (S1), 217, p. 115A - 115A. 67th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), Boston, MA, November 11, 2016 - November 15, 2016. Wiley - American Association for the Study of Liver Diseases (2016)

Kaps, L.; Nuhn, L.; Aslam, M.; Brose, A.; Foerster, F.; Zentel, R.; Schuppan, D.: In Vivo Myofibroblast Specific Gene Silencing in the Liver Using Novel Sirna-Loaded Biodegradable Nanohydrogel Particles. In Journal of Hepatology, 64 (S2), FRI-015, p. S448 - S448. EASL International Liver Congress, Barcelona, Spain, April 13, 2016 - April 17, 2016. Elsevier, Amsterdam (2016)

Nuhn, L.; Leber, N.; Zentel, R.: Cationic nanohydrogel particles as carriers for therapeutic oligonucleotide delivery. In Abstracts of Papers of the American Chemical Society, 251 (POLY), 512. 251st ACS National Meeting, San Diego, CA, March 10, 2016 - March 18, 2016. (2016)

Nuhn, L.; Vanparijs, N.; De Geest, B.: Biomimetic vaccine nanogels for cell-uptake-triggered immune activation. In Abstracts of Papers of the American Chemical Society, 251 (PMSE), 122. 251st ACS National Meeting, San Diego, CA, March 13, 2016 - March 17, 2016. (2016)